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Stress ReliefTM

Stress & Anxiety Inhibitor

$37.47


100 Tablets     Natural Anti-Stress Formula

  • Reduces stress and anxiety*
  • Promotes better sleep and general relaxation*
  • Boosts immune system*
  • Tab 1

     

    • Reduces stress and anxiety
    • Promotes better sleep and general relaxation
    • Helps the body keep up with physical and environmental pressures
    • Improves appetite
    • Boosts immune system to fight off infections and diseases
    • Aids in the maintenance of overall health generally lost during periods of stress and anxiety 

    Biogenique StresStop is a natural, synergistic formula of calming and soothing herbs combined with B group vitamins and essential minerals. The herbs used are called "adaptogens" as they help the body deal with and “adapt” to various forms of daily stresses. Simultaneously, vitamins and minerals work together to prevent nutritional losses whilst boosting energy levels and endurance during low periods. Biogenique StresStop provides a unique, comprehensive solution that allows for stress and anxiety problems to be managed naturally and holistically. 

    Why Biogenique?


    The application of Structurally Active-Orthogenic (SAO) technology by Biogenique’s research and production team ensures that all available products are of a heightened quality. 

    SAO technology produces active ingredients with strong molecular composition and the highest bioavailability (ratio of inactive/active ingredients) in order to ensure synergistic applications occur within the body. In other words, the Biogenique label ensures that all our products are able to be optimally absorbed by the bloodstream at the molecular level, and don’t just pass through the body undigested. 

    Biogenique is pharmaceutically tested and clinically verified by careful examination at every stage of production. The protocols are measured and confirmed for international standard compliance before the product is introduced to market. 

    Biogenique only uses 100% natural ingredients. 




    Tab 1

    Active Ingredients


    Lemon balm..................................................................................................100mg 
    Ashwagandha (Dried roots)............................................................................75mg
    Valerian (Dried roots).....................................................................................75mg
    Ginseng (Dried roots)...................................................................................100mg 
    Quercetin........................................................................................................30mg
    Roseroot (Rhodiola Rosea, Root)...................................................................75mg
    Vitamin B1 (Thiamine Mononitrate)................................................................5mg
    Vitamin B2 (Riboflavin)....................................................................................3mg
    Vitamin B3 (Niacinamide)...............................................................................15mg
    Vitamin B5 (Calcium D-Pantothenate).............................................................5mg
    Vitamin B6 (Pyridoxal Hydrochloride).............................................................3mg
    Vitamin B12..................................................................................................15mcg
    Vitamin C (Citrus Aurantium - Fruit)...........................................................300mg
    Biotin.............................................................................................................10mcg
    Folic acid (Folate).........................................................................................50mcg
    Magnesium (Magnesium Oxide, Oryza sativa - Seed)....................................50mg 

     

     



    Tab 3

    Stress ReliefTM

     

    NPN:

     

    80046472 

     

    Quantity:


    100 Tablets

     

     

    Non Medicinal Ingredients:

     

    Vegetable microcrystalline cellulose, vegetable croscarmellose sodium, dibasic calcium phosphate vegetable grade, natural anise flavor, silicon dioxide vegetable grade, vegetable htpromellose.

     

    This Product Does Not Contain:


    Gelatin, gluten, sugar, dairy or preservatives. 

    Recommended Use:


    Relieves stress and helps in the maintenance of good health. 

    Recommended Dose:


    Adults: Take 1-2 tablet(s) daily with food. Don't take immediately before bedtime . 

    Risk Information:

     

    Cautions & Warnings:


    Consult a healthcare practitioner if symptoms persist or worsen, if you are taking blood thinners, digoxin, antidepressant medication, birth control pills, hormone replacement therapy, of if you are pregnant, breastfeeding or diabetic.

    Keep out of reach of children. 

    Contraindications:


    Do not use if you have bipolar disorder spectrum disorder. 

    Known Adverse Reactions:


    Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Discontinue use if you experience irritability or insomnia. 

     

    Storage:


    • Seal for tamper resistant protection.
    • If Seal is broken do not use.
    • Store at room temperature 15-30 C
    • Protect from Moisture 

    download monograph

     

     





    Tab 3

    Tab 3 Content

    Tab 1

    Background


    American ginseng (Panax quinquefolius), Lemon balm (Melissa officinalis), Roseroot (rhodiola rosea) and Valerian (valeriana officinalis) are calming, soothing herbs together called as “adaptogens”. They are often used in combination to help reduce anxiety and promote relaxation and sleep. 

    Biogenique Structurally Active-Orthogenic (SAO) technology


    Biogenique SAO technology formulates Strestop with synergistic combination of herbs with water soluble B group vitamins and minerals. The herbs are derived from natural and authentic sources. Their medicinal properties are well intact and not lost during the process of extraction of active chemical compounds from herbs. 

    The B vitamins are a chemically related family of nutrients that work as a team. To get the most benefits from any of B’s vitamin you need all of them. B vitamins are water-soluble vitamins, meaning that the body does not store them. Therefore, they should be replenished daily for optimal health from food or supplements. They metabolise carbohydrates, fats and proteins to produce energy and relieves from stress, anxiety and depression. 

    Biogenique SAO technology uses vitamin B3 in niacinamide form over niacin form, as it is well absorbed and likely safe. A common minor side effect of niacin is a flushing reaction - causing burning, tingling, itching, and redness of the face, arms, and chest, as well as headaches. 

    The minerals like magnesium relaxes muscles, stabilises abnormal nerve excitement and specifically indicated for insomnia due to stress and unwanted thoughts. 

    SAO technology establishes a higher caliber of science for better quality research and formulation. It makes sure that the compounds are delivered on their potential to create effectiveness. 

    SAO Analysis


    American ginseng (Panax quinquefolius):
    American ginseng products are made from ginseng root and the long, thin offshoots called root hairs. The main chemical ingredients of American ginseng are ginsenosides and polysaccharide glycans (quinquefolans A, B, and C). American ginseng seems to be more relaxing than Asian ginseng, which may have stimulating effects. American ginseng is very expensive and is endangered in the wild. It is now being grown on farms to protect wild American ginseng from over-harvesting. 

    Lemon balm (Melissa officinalis)
    Lemon balm supplements are made from the leaves of the plant. Essential oils made from lemon balm leaves contain plant chemicals called terpenes, which play at least some role in the herb's relaxing and antiviral effects. Lemon balm also contains substances called tannins, which may be responsible for many of the herb's antiviral effects. Lemon balm also contains eugenol, which calms muscle spasms, numbs tissues, and kills bacteria. 

    Roseroot (rhodiola rosea)
    Rhodiola is a plant. The root is used as medicine. Rhodiola is native to the arctic regions of Europe, Asia, and Alaska. It has a long history of use as a medicinal plant in Iceland, Sweden, France, Russia, and Greece. Rhodiola extracts might help protect cells from damage, regulate heartbeat, and have the potential for improving learning and memory. Rhodiola is used for increasing energy, stamina, strength and mental capacity; and as a so-called “adaptogen” to help the body adapt to and resist physical, chemical, and environmental stress. 

    Valerian (valeriana officinalis)
    Valerian is a powerful nervine, stimulant, carminative and antispasmodic. It has a remarkable influence on the cerebro-spinal system, and is used as a sedative to the higher nerve centres in conditions of nervous unrest, hypochondriasis, neuralgic pains and the like. The drug allays pain and promotes sleep. It is of especial use and benefit to those suffering from nervous overstrain, as it possesses none of the after-effects produced by narcotics. The juice of the fresh root is of value as a narcotic in insomnia, and as an anti-convulsant in epilepsy. Having also some slight influence upon the circulation, slowing the heart and increasing its force, it has been used in the treatment of cardiac palpitations. 

    Scientific Evidence


    Insomnia and anxiety

    Several studies show that lemon balm combined with other calming herbs helps reduce anxiety and promote sleep. Few studies have examined lemon balm by itself, except for topical use. For example, in one study of people with minor sleep problems, 81% of those who took an herbal combination of valerian and lemon balm reported sleeping much better than those who took placebo. But it's not clear from this and other studies whether lemon balm or valerian (or the combination) is responsible for the result. The same is true of several studies for anxiety, which used a combination of herbs to reduce symptoms. In another double blind, placebo controlled study, 18 healthy volunteers received single dose of a standardized lemon balm extract or placebo for 7 days. The results were, lemon balm increased mood and significantly increased calmness and alertness. 

    Immune system enhancement

    Some scientists believe American ginseng enhances the immune system. In theory, this improvement in immune function could help the body fight off infection and disease. Several clinical studies have shown that American ginseng does boost the performance of cells playing a role in immunity. 

    Stress

    The B vitamins are generally associated with brain and nervous-system function. Vitamin B6, pyridoxine, may affect mood by its ability to process beneficial series-one prostaglandins, which have a variety of roles in regulating cellular activities such as the inflammatory response.

    Depression

    Because a key enzyme in the synthesis of neurotransmitters serotonin and norepinephrine is PLP-dependent, it has been suggested that vitamin B6 deficiency can lead to depression. Vitamin B6 supplementation may have a therapeutic efficacy in premenopausal women. It may even benefit people in dysphoric mental states. 

    Safety


    • The use of herbs is a time honored approach to strengthening the body and treating disease. Herbs, however, contain components that can trigger side effects and interact with other herbs, supplements, or medications. For these reasons, you should take herbs with care, under the supervision of a health care provider qualified in the field of botanical medicine.

    • Pregnant and breastfeeding women should not take Strestop.

    • Side effects are rare but may include: High blood pressure, Insomnia, Restlessness, Anxiety, Euphoria, Diarrhea, Vomiting, Headache, Nosebleed, Breast pain and Vaginal bleeding

    • People with hypertension (high blood pressure) should not take American ginseng products without the close supervision of their doctor. At the same time, people with low blood pressure, as well as those with an acute illness, should use caution when taking American ginseng.

    • People with bipolar disorder should not take ginseng, because it may increase the risk of mania. 

    Interactions you should know


    • Sedatives, thyroid medications -- Lemon balm may interact with sedatives and thyroid medications. If you are taking sedatives (for insomnia or anxiety) or medications to regulate your thyroid, ask your doctor before taking lemon balm. 

    • Medications for diabetes -- American ginseng may lower blood sugar levels, so it could interfere with the effectiveness of prescription drugs for diabetes. Talk to your doctor before taking American ginseng if you are taking medicines for diabetes, including insulin and oral hypoglycemic agents such as metformin (Glucophage).

    • Blood-thinning medications (anticoagulants) -- One small study suggested that American ginseng might decrease the effectiveness of warfarin (Coumadin), a blood thinning medication. If you take any blood-thinning medications, ask your doctor before taking ginseng.

    • Antipsychotic medications -- American ginseng may increase the effects of medications used to treat psychiatric disorders such as schizophrenia and bipolar disorder, so they should not be taken together 

    Selected references


    1. Andrade AS, Hendrix C, Parsons TL, Caballero B, Yuan CS, Flexner CW, et al. Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir. BMC Complement Altern Med. 2008 Aug 19;8:50.

    2. Ang-Lee MK, Moss J, Yuan C-S. Herbal medicines and perioperative care. JAMA. 2001;286(2):208-216.

    3. Banz WJ, Iqbal MJ, Bollaert M, Chickris N, James B, Higginbotham DA, et al. Ginseng modifies the diabetic phenotype and genes associated with diabetes in the male ZDF rat. Phytomedicine. 2007 Oct;14(10):681-9.

    4. Barton DL, Soori GS, Bauer BA, Sloan JA, Johnson PA, Figueras C, Duane S, Mattar B, Liu H, Atherton PJ, Christensen B, Loprinzi CL. Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA. Support Care Cancer. 2010;18(2):179-87

    5. Biondo PD, Robbins SJ, Walsh JD, McCargar LJ, Harber VJ, Field CJ. A randomized controlled crossover trial of the effect of ginseng consumption on the immune response to moderate exercise in healthy sedentary men. Appl Physiol Nutr Metab. 2008 Oct;33(5):966-75.

    6. Ballard CG, O'Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry. 2002;63(7):553-8.

    7. Berdonces JL. Attention deficit and infantile hyperactivity. [Spanish]. Rev Enferm. 2001;24(1):11-14.

    8. Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000:230-232.

    9. de Sousa AC, Alviano DS, Blank AF, Alves PB, Alviano CS, Gattass CR. Melissa officinalis L. essential oil: antitumoral and antioxidant activities. J Pharm Pharmacol. 2004;56(5):677-81.

    10. Dos Santos-Neto LL, de Vilhena Toledo MA, Medeiros-Souza P, de Souza GA. The use of herbal medicine in Alzheimer's disease-a systematic review. Evid Based Complement Alternat Med. 2006 Dec;3(4):441-5.

    11. Ernst E. The Desktop Guide to Complementary and Alternative Medicine: An Evidence-Based Approach. Mosby, Edinburgh; 2001:169 




    Tab 3

    I)Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility.


    Source

    Ruder EH1, Hartman TJ2, Reindollar RH3, Goldman MB4. 

    ABSTRACT

    OBJECTIVE: 

    To determine whether increased antioxidant intake in women is associated with shorter time to pregnancy (TTP) among a cohort of couples being treated for unexplained infertility. 

    DESIGN: 

    Secondary data analysis of a randomized controlled trial. 

    SETTING: 

    Academic medical center associated with a private infertility center. 

    PATIENTS: 

    Females with unexplained infertility. 

    INTERVENTIONS: 

    None. 

    MAIN OUTCOME MEASURE(S): 

    The time it took to establish a pregnancy that led to a live birth. 

    RESULTS: 

    Mean nutrient intake exceeded the estimated average requirement (EAR) for vitamins C and E. No differences in mean intake of any of the antioxidants were noted between women who delivered a live-born infant during the study period vs. those who did not. In multivariable models, intake of β-carotene from dietary supplements was associated with shorter TTP among women with body mass index (BMI) ≥25 kg/m2 (hazard ratio [HR] 1.29, 95% confidence interval [CI] 1.09-1.53) and women
    CONCLUSION: 

    Shorter TTP was observed among women with BMI

     

    II)Seasonal Variation of 25-Hydroxyvitamin D among non-Hispanic Black and White Pregnant Women from Three US Pregnancy Cohorts.


    Source

    Luque-Fernandez MA, Gelaye B, Vanderweele T, Ferre C, Siega-Riz AM, Holzman C, Enquobahrie DA, Dole N, Williams MA. 

    ABSTRACT

    BACKGROUND: 

    Vitamin D deficiency during pregnancy has been associated with increased risk of complications and adverse perinatal outcomes. We evaluated seasonal variation of 25-hydroxyvitamin D [25(OH)D] among pregnant women, focusing on patterns and determinants of variation. 

    METHODS: 

    Data came from three cohort studies in the US that included 2583 non-Hispanic Black and White women having prenatal 25(OH)D concentrations determined. Fourier time series and generalised linear models were used to estimate the magnitude of 25(OH)D seasonality. We modelled seasonal variability using a stationary cosinor model to estimate the phase shift, peak-trough difference, and annual mean of 25(OH)D. 

    RESULTS: 

    We observed a peak for 25(OH)D in summer, a nadir in winter, and a phase of 8 months, which resulted from fluctuations in 25(OH)D3 rather than 25(OH)D2. After adjustment for covariates, the annual mean concentrations and estimated peak-trough difference of 25(OH)D among Black women were 19.8 ng/mL [95% confidence interval (CI) 18.9, 20.5] and 5.8 ng/mL [95% CI 4.7, 6.7], and for non-Hispanic White women were 33.0 ng/mL [95% CI 32.6, 33.4] and 7.4 ng/mL [95% CI 6.0, 8.9]. 

    CONCLUSION: 

    Non-Hispanic Black women had lower average 25(OH)D concentrations throughout the year and smaller seasonal variation levels than non-Hispanic White women. This study's confirmation of 25(OH)D seasonality over a calendar year has the potential to enhance public health interventions targeted to improve maternal and perinatal outcomes. © 2013 John Wiley & Sons Ltd. 

    III)Weekly dose of Iron-Folate Supplementation with Vitamin-C in the workplace can prevent anaemia in women employees.


    Source

    Joseph B1, Ramesh N2. 

    ABSTRACT

    OBJECTIVE: 

    To assess if a weekly dose of iron and folic acid along with vitamin C, in the workplace would reduce the prevalence of anaemia. Methodology: A multi-pronged intervention was carried out to reduce the prevalence of anaemia among workers of 7 apparel manufacturing factories using a regime consisting of a supervised single dose of albendazole (400mg) followed by a weekly dose of dried ferrous sulphate (150mg), folic acid (0.5mg) and vitamin C (100mg). Workers were provided information on the causes of anaemia and its prevention. The total duration of the intervention was 16 weeks. Haemoglobin levels of a randomly selected sample of workers were tested before and after the intervention using a computerized non-cyan-meth-haemoglobin method. Results: Of the 10810 workers who were enrolled a sample of 515 workers was randomly selected for the blood investigations. At the end of the intervention (18 weeks after the first blood sample was collected) only 361 out of the 515 who had been enrolled a little more than 16 weeks earlier still remained in the factories and among women 279 out of 385 enrolled were still working in the factories. In the 385 unmatched samples the number of anaemic women had reduced from 141 before the intervention to 79 after - mean haemoglobin increasing from 12.2 to 13.0 (p < 0.001) and in the 279 paired samples prevalence of anaemia had reduced from 105 to 58 - mean haemoglobin increasing from 12.1 to 13.0 (p < 0.001). Conclusions: Our results demonstrated that in resource poor regions, where prevalence of anaemia is high, the workplace may be considered an ideal location to give a weekly supervised dose of iron, folic acid and vitamin C to effectively tackle the problem and probably improve worker efficiency. 







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